Bone Restore with Vitamin K2, 120 capsules - Life Extension

Health Benefits at a Glance:

Bone Restore with Vitamin K2 can contribute to keeping calcium, magnesium boron, zinc, manganese, silicon, Vitamin D3 and K2 balance within normal range.  As we age we may experience loss in bone density, why it is important to support healthy bones and postpone the natural aging process.

Why it Works:

Although calcium is the most abundant mineral in the body and is a key component in building bone and teeth, most people don’t get enough calcium to offset the amount being lost over the course of aging.

Postmenopausal women commonly experience loss of bone mineral density but older men can also face this issue [1].

Moreover, many forms of calcium are not well-absorbed [2-4]. Bone Restore with Vitamin K2 provides three types of calcium which are easy for the body to absorb; dicalcium malate, calcium fructoborate, and calcium bisglycinate chelate come in capsule form to ensure that it breaks down in the digestive tract easily.

Loss of bone density is not just associated with calcium deficiency alone. An insufficient intake of many other nutrients [5-12] including magnesium [11,12] and vitamin D3 [13,14] can also play a role in bone density loss. In order for calcium to help maintain healthy bones, adequate amounts of magnesium [15] zinc [16,17] manganese [10,18] vitamin D3, and other nutrients should be available in the body so that calcium and phosphorus can be used to build bone strength.

The Science Behind the Product:

Scientific research has demonstrated the beneficial effects of the trace mineral boron on the strength of bones and joints [6,19-22]. Bone Restore with Vitamin K2 formula contains patented Fruitex B® OsteoBoron®, a potent form of boron made from a calcium/carbohydrate/boron complex. Fruitex B® OsteoBoron® has been shown to be more bioavailable than boron citrate, the nutrient used in most commercial bone building supplements.

Human clinical data demonstrates that vitamin K is important in maintaining healthy bone density by facilitating the transport of calcium from the bloodstream into the bones [23-27]. Insufficient intake of vitamin K can lead to increased circulation levels of undercarboxylated osteocalcin. This has been linked with poor bone condition in post-menopausal women [28,29].

Studies have revealed that vitamin K2 is more bioavailable than vitamin K1. Recently, two forms of vitamin K2 have been extensively investigated and the findings revealed improved effects of vitamin K2 compared to vitamin K1. The MK-7 (menaquinone-7) form of K2 can stay at a higher level in the body and accumulates at greater levels (seven- to eight-fold) during prolonged intake [27].

How to Use:

• Take four (4) capsules daily, or as recommended by a healthcare practitioner.

Scientific studies suggest calcium supplementation in divided doses with food in the morning and evening may yield the best results.

Maintaining an optimal vitamin D blood level also helps maximize calcium absorption.

Reference List:

1. Osteoporos Int. 2009 Jul;20(7):1175-82.
2. J Nutr Sci Vitaminol (Tokyo). 1999 Oct;45(5):509-17.
3. Methods Find Exp Clin Pharmacol. 1995 Sep;17(7):437-42.
4. Scand J Gastroenterol. 2010;45(2):133-8.
5. Crit Rev Food Sci Nutr. 2006;46(8):621-8.
6. Magnes Trace Elem. 1990;9(2):61-9.
7. Curr Pharm Des.2003;9(32):2687-704.
8. Ann Nutr Metab. 2002;46(6):249-53.
9. J Int Med Res. 2007 Sep-Oct;35(5):692-5.
10. J Nutr. 1994 Jul;124(7):1060-4.
11. Magnes Res. 1993 Jun;6(2):155-63.
12. J Reprod Med. 1990 May;35(5):503-7.
13. J Clin Endocrinol Metab. 2010 Jun;95(6):2630-3.
14. Am J Clin Nutr. 1995 Mar;61(3 Suppl):638S-45S.
15. PDR for Nutritional Supplements, 1st ed. Montvale, NJ: Medical Economics Co.; 2001:288-95.
16. Ann Nutr Metab. 2009;54(3):218-26.
17. Toxic Sci. 2006 Jul;92(1):286-94.
18. Clin Chem Lab Med. 2013 Aug;51(8):1555-61.
19. Environ Health Perspect. 1994 Nov;102 Suppl 7:83-5.
20. Crit Rev Food Sci Nutr. 2003;43(2):219-31.
21. Prog Food Nutr Sci. 1993 Oct-Dec;17(4):331-49.
22. Nutr Rev. 2008 Apr;66(4):183-91
23. J Bone Miner Metab. 2001;19(3):146-9.
24. Osteoporos Int. 2007 Jul;18(7):963-72.
25. J Bone Miner Res. 2007 Apr;22(4):509-19.
26. Natural Vitamin K2 as Menaquinone-7. Monograph April 2006
27. Blood. 2007 Apr 15;109(8):3279-83.
28. Vitam Horm. 2008;78:393-416.
29. Curr Drug Saf. 2006 Jan;1(1):87-97.